George Mason University
George Mason University Mason
George Mason University

Germaine Louis, PhD, MS

Dean, College of Health and Human Services

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Dr. Germaine M. Buck Louis is an internationally recognized reproductive and perinatal epidemiologist whose expertise focuses on environmental influences on human fecundity and fertility.  Her research has focused on a mixture of environmental exposures, including endocrine disrupting chemicals, stress and lifestyle in relation to a spectrum of reproductive outcomes in both men and women.  In addition, Dr. Buck Louis’ research continues to focus on the implications of fecundity and fertility for health across the lifespan.  A complimentary and parallel avenue of research includes methods aimed at addressing challenges, such as the complexity associated with studying environmental mixtures and the clustering of reproductive outcomes.  She is an early pioneer in the application of the exposome research paradigm for understanding environmental influences on human fecundity and fertility impairments.  During her career, she has served as Principal Investigator for original extramural and intramural research totally over $53 million.

Prior to becoming the Dean of the College of Health and Human Services in October 2017, Dr. Buck Louis was the Director for the Division of Intramural Population Health Research at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health.  This position was preceded by her role as a tenured professor in the Department of Social and Preventive Medicine, University of Buffalo, School of Medicine and Biomedical Sciences, where she taught in both the graduate and medical schools.  She has published numerous scientific papers and technical reports, and co-edited the textbook Reproductive and Perinatal Epidemiology.  She has provided considerable service to The National Academies, Pan American Health Organization, U.S. Environmental Protection Agency, and World Health Organization among other governmental agencies.  She has been the President of the Society for Pediatric and Perinatal Epidemiologic Research, President of the Society for Epidemiologic Research and Councilor for the International Society for Environmental Epidemiology.  Currently, Dr. Buck Louis serves on the Board for the American College of Epidemiology and the Board on Environmental Studies and Toxicology (BEST), National Academies of Sciences, Engineering and Medicine.  Dr. Buck Louis is the recipient of many awards for research excellence, mentoring and service. 


PhD, Epidemiology, State University of New York at Buffalo

MS, Epidemiology, State University of New York at Buffalo

Personal Websites:


Research Interests

  • Human reproduction and development
  • Environmental influences on human fecundity and fertility
  • Endocrine disruptors
  • Exposome
  • Research methods

Select Publications, 2018-2019

Buck Louis GM, Bell E, Xie Y, Sundaram R, Yeung E. Parental health and infant outcomes, Upstate KIDS Study. Fertility and Sterility. 2018;109(2):315-323. PMID: 29338856

Grewal J, Grantz KL, Zhang C, Sciscione A, Wing DA, Grobman WA, Newman RB, Wapner R, D’Alton ME, Skupski D, Nageotte MP, Ranzini AC, Owen J, Chien EK, Craigo S, Albert PS, Kim S, Hediger ML, Buck Louis GM. Cohort profile. NICHD Fetal Growth Studies – singletons and twins. International Journal of Epidemiology. 2018;47(1):25-25i. PMID: 29025016

Sapra KJ, Buck Louis GM, Sundaram R, Joseph KS, Bates LM, Galea S, Ananth CV. Time-varying effects of signs and symptoms on pregnancy loss <20 weeks: Findings from a preconception prospective cohort study. Paediatric and Perinatal Epidemiology. 2018;32(1):30-39. PMID: 29336062

Zhang C, Hediger ML, Albert PS, Grewal J, Sciscione A, Grobman WA, Wing DA, Newman RB, Wapner R, D’Alton ME, Skupski D, Nageotte MP, Ranzini AC, Owen J, Chien EK, Craigo S, Kim S, Grantz KL, Buck Louis GM. Association of maternal obesity with longitudinal ultrasonographic measures of fetal growth:  findings from the NICHD Fetal Growth Studies – Singletons. JAMA Pediatrics. 2018;172(1):24-31. PMID: 29131898

Nobles CJ, Schisterman EF, Ha S, Buck Louis GM, Sherman S, Mendola P. Time-varying cycle average and daily variation in ambient air pollution and fecundability. Human Reproduction. 2018;33(1):166-176. PMID: 29136143

Buck Louis GM, Smarr MM, Sun L, Chen Z, Honda M, Wang W, Karthikraj R, Weck, Kannan K. Endocrine disrupting chemicals in seminal plasma and couple fecundity. Environmental Research. 2018;163:64-70. PMID: 29426029

Lynch CD, Sundaram R, Buck Louis GM. Biomarkers of preconception stress and the incidence of pregnancy loss. Human Reproduction. 2018; 33(4):728-735. PMID 29490045

Smarr MM, Honda M, Kannan K, Chen Z, Kim S, Buck Louis GM. Male urinary biomarkers of antimicrobial exposure and bi-directional associations with semen quality parameters. Reproductive Toxicology. 2018;77:103-108. PMID: 29474822

Workalemahu T, Grantz KL, Grewal J, Zhang C, Buck Louis GM, Tekola-Ayele F. Genetic and environmental influences on fetal growth vary during sensitive periods in pregnancy. Scientific Reports. 2018;8(1):7274. PMID: 29740100

Gaskins AJ, Chavarro JE, Sundaram R, Buck Louis GM. Seafood intake, sexual activity and time-to-pregnancy. Journal of Clinical Endocrinology and Metabolism. 2018;103(7):2680-2688. PMID: 29800287

Smarr MM, Kannan K, Sun L, Honda M, Wang W, Karthikraj R, Chen Z, Weck J, Buck Louis GM.  Preconception seminal plasma concentrations of endocrine disrupting chemicals in relation to semen quality parameters among male partners planning for pregnancy. Environmental Research. 2018;167:78-86. PMID: 30014899

Buck Louis GM, Zhai S, Smarr SM, Grewal J, Zhang C, Grantz KL, Hinkle SN, Sundaram R, Lee S, Honda M, Oh JK, Kannan K. Endocrine disruptors and neonatal anthropometry, NICHD Fetal Growth Studies – singletons. Environment International. 2018;119:515-526. PMID: 30055518

Chung MK, Kannan K, Buck Louis GM, Patel CJ. Toward capturing the exposome: exposure biomarker variability and co-exposure patterns in the shared environment. Environment, Science and Technology. 2018;52(15):8801-8810. PMID: 29972023

Bell EM, Yeung EH, Ma W, Kannan K, Sundaram R, Smarr MM, Buck Louis GM. Concentrations of endocrine disrupting chemicals in newborn blood spots and infant outcomes in the Upstate KIDS Study. Environment International 2018;121:232-239. PMID: 30219610

Ghassabian A, Bell EM, Ma W-L, Sundaram R, Kannan K, Buck Louis GM, Yeung E. Concentrations of perfluoroalkyl substances and bisphenol A in newborn dried blood spots and the association with child behavior. Environmental Pollution. 2018;243 (part B):1629-1636. PMID: 30296759

Choi G, Wang Y-B, Sundaram R, Chen Z, Barr DB, Buck Louis GM, Smarr MM. Polybrominated diphenyl ethers and incident pregnancy loss:  The LIFE Study. Environmental Research. 2019;168:375-381. PMID: 30384231

Wang Yu-Bo, Chen Z, Goldstein JM, Buck Louis GM, Gilman, SE. A Bayesian regularized mediation analysis with multiple exposures. Statistics in Medicine. 2019;38:828-843. PMID: 30375022

Chung MK, Buck Louis GM, Kannan K, Patel CJ. Exposome-wide association study of semen quality: systematic discovery of endocrine disrupting chemical biomarkers in fertility require large sample sizes. Environment International. 2019;125:505-514. PMID: 30583854

Rahman M, Zhang C, Smarr MM, Lee S, Honda M, Kannan K, Ayele-Tekola F, Buck Louis GM. Persistent organic pollutants and gestational diabetes: A multi-center prospective cohort study of healthy US women. Environment International. 2019;124:249-258. PMID: 30660025

Smarr MM, Bible J, Gerlanc N, Buck Louis GM, Bever A, Grantz KL. Comparison of fetal growth by maternal prenatal acetaminophen use. Pediatric Research. 2019 Aug;86(2):261-268. PMID: 30911064

Hwang BS, Chen Z, Buck Louis GM, Albert P. A Bayesian multi-dimensional couple-based latent risk model with an application to infertility. Biometrics. 2019;75(1)315-325. PMID: 26295923

Buck Louis GM, Yeung E, Kannan K, Maisog J, Zhang C, Grantz K, Sundaram R. Patterns and variability of endocrine disrupting chemicals during pregnancy: Implications for understanding the exposome of normal pregnancy. Epidemiology. 2019;30 (suppl 2):S65-S75. PMID: 31569155

Tekola-Ayele F, Workalemahu T, Gorfu G, Shrestha D, Tycko B, Wapner R, Zhang C, Buck Louis GM. Sex differences in the associations of placental epigenetic aging with fetal growth. Aging. 2019; 11(15):5412-5432. PMID: 31395791

Kim S, Chen Z, Perkins NJ, Schisterman EF, Buck Louis GM. A model-based approach to detection limits in studying environmental exposures and human fecundity. Statistics in Biosciences. Published online June 7, 2019. DOI 10.1007/S12561-019-09232-5.

Ouidir M, Buck Louis GM, Kanner J, Grantz KL, Zhang C, Sundaram R, Rahman ML, Lee S, Kannan K, Tekola-Ayele F, Mendola P. Persistent organic pollutant exposure during early pregnancy and longitudinal fetal growth in the NICHD Fetal Growth Studies - Singletons. JAMA Pediatrics. 2019. Published online December 30, 2019.

Honors & Awards

NICHD Collaboration Award, 2017, Eunice Kennedy Shriver National Institute of Child Health & Human Development

Society for Pediatric & Perinatal Research President’s Inaugural Award, 2014, Society for Pediatric & Perinatal Research

NIH Mentoring Award, 2004, National Institutes of Health

Service Award, 2000, International Society for Environmental Epidemiology

Abraham Lilienfeld Award, 1987, Society for Epidemiologic Research

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