Germaine Louis, PhD, MS
Dr. Germaine M. Buck Louis is an internationally recognized reproductive and perinatal epidemiologist whose expertise focuses on environmental influences on human fecundity and fertility. Her research has focused on a mixture of environmental exposures, including endocrine disrupting chemicals, stress and lifestyle in relation to a spectrum of reproductive outcomes in both men and women. In addition, Dr. Buck Louis’ research continues to focus on the implications of fecundity and fertility for health across the lifespan. A complimentary and parallel avenue of research includes methods aimed at addressing challenges, such as the complexity associated with studying environmental mixtures and the clustering of reproductive outcomes. She is an early pioneer in the application of the exposome research paradigm for understanding environmental influences on human fecundity and fertility impairments. During her career, she has served as Principal Investigator for original extramural and intramural research totally over $53 million.
Prior to becoming the Dean of the College of Health and Human Services in October 2017, Dr. Buck Louis was the Director for the Division of Intramural Population Health Research at the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health. This position was preceded by her role as a tenured professor in the Department of Social and Preventive Medicine, University of Buffalo, School of Medicine and Biomedical Sciences, where she taught in both the graduate and medical schools. She has published numerous scientific papers and technical reports, and co-edited the textbook Reproductive and Perinatal Epidemiology. She has provided considerable service to The National Academies, Pan American Health Organization, U.S. Environmental Protection Agency, and World Health Organization among other governmental agencies. She has been the President of the Society for Pediatric and Perinatal Epidemiologic Research, President of the Society for Epidemiologic Research and Councilor for the International Society for Environmental Epidemiology. Currently, Dr. Buck Louis serves on the Board for the American College of Epidemiology and the Board on Environmental Studies and Toxicology (BEST), National Academies of Sciences, Engineering and Medicine. Dr. Buck Louis is the recipient of many awards for research excellence, mentoring and service.
PhD, Epidemiology, State University of New York at Buffalo
MS, Epidemiology, State University of New York at Buffalo
- Human reproduction and development
- Environmental influences on human fecundity and fertility
- Endocrine disruptors
- Research methods
Refereed Publications 2019
Choi G, Wang Y-B, Sundaram R, Chen Z, Barr DB, Buck Louis GM, Smarr MM. Polybrominated diphenyl ethers and incident pregnancy loss: The LIFE Study. Environmental Research. 2019;168:375-381. PMID: 30384231
Zhang W, Chen Z, Liu A, Buck Louis GM. A weighted kernel machine regression approach to environmental pollutants and infertility. Statistics and Medicine 2019;38:809-827. PMID: 30328128
Wang Yu-Bo, Chen Z, Goldstein JM, Buck Louis GM, Gilman, SE. A Bayesian regularized mediation analysis with multiple exposures. Statistics in Medicine 2019;38:828-843. PMID: 30375022
Chung MK, Buck Louis GM, Kannan K, Patel CJ. Exposome-wide association study of semen quality: systematic discovery of endocrine disrupting chemical biomarkers in fertility require large sample sizes. Environment International 2019;125:505-514. PMID: 30583854
Hemmert R, Schliep KC, Willis S, Peterson CM, Buck Louis GM, Allen-Brady K, Simonsen S, Stanford J, Willis S, Byun J, Smith K. Modifiable lifestyle factors and risk for incident endometriosis. Paediatric and Perinatal Epidemiology 2019;33:19-25. PMID: 30307628
Rahman M, Zhang C, Smarr MM, Lee S, Honda M, Kannan K, Ayele-Tekola F, Buck Louis GM. Persistent organic pollutants and gestational diabetes: A multi-center prospective cohort study of healthy US women. Environment International 2019;124:249-258. PMID: 30660025
Owens J, Albert PS, Buck Louis GM, Fuchs KM, Grobman WA, Kim S, D’Alton ME, Wapner R, Wing DA, Grantz KL. A contemporary amniotic fluid volume standard for the United States: the NICHD Fetal Growth Studies – Singletons. American Journal of Obstetrics & Gynecology. 2019;21(1);e1-67. PMID: 30790566
Mills JL, Mehnaz A, Buck Louis GM, Kannan K, Weck J, Wan Y, Maisog J, Giannakou A, Sundaram R. Pregnancy loss and iodine status: The LIFE Prospective Cohort Study. Nutrients 2019;11:534. PMID: 30823683
Smarr MM, Bible J, Gerlanc N, Buck Louis GM, Bever A, Grantz KL. Comparison of fetal growth by maternal prenatal acetaminophen use. Pediatric Research. 2019 Aug;86(2):261-268. PMID: 30911064
Hwang BS, Chen Z, Buck Louis GM, Albert P. A Bayesian multi-dimensional couple-based latent risk model with an application to infertility. Biometrics. 2019;75(1)315-325. PMID: 26295923
Grewal J, Buck Louis GM, Hinkle S, Mumford SL, Lu Y-L, Nansel TR, Perkins N, Mills J, Liu A, Schisterman EF. Advancing the health of populations across the life course: 50 years of discoveries in the Division of Intramural Population Health Research. Epidemiology. 2019;30, Suppl 2:S47-S54. PMID: 31569152
Kahn LG, Widen EM, Janevic T, Straka N, Liu X, Cirillo PM, Cohn BA, Buck Louis GM, Factor-Litvak P. The relation of birth weight and adiposity across the life course to semen quality in middle age. Epidemiology. 2019;20, Suppl 2:S17-S27. PMID: 31569149
Yeung E, Bell E, Sundaram R, Ghassabian A, Ma W, Kannan K, Buck Louis GM. Examining endocrine disruptors measured in newborn dried blood spots and early childhood growth in a prospective cohort. Obesity. 2019;27(1):145-152. PMID: 3056934
Bell GA, Perkins N, Buck Louis GM, Kannan K, Bell EM, Yeung EH. Exposure to persistent organic pollutants and birth weight: The Upstate KIDS Study. Epidemiology. 2019;30, Suppl 2:S94-S100. PMID: 31569158
Buck Louis GM, Yeung E, Kannan K, Maisog J, Zhang C, Grantz K, Sundaram R. Patterns and variability of endocrine disrupting chemicals during pregnancy: Implications for understanding the exposome of normal pregnancy. Epidemiology. 2019;30 (suppl 2):S65-S75. PMID: 31569155
Zheng Y, Zhang C, Weisskopf M, Williams PL, Parsons PJ, Palmer CD, Buck Louis GM, James-Todd T. Early pregnancy metal(loid)s concentrations and gestational glucose levels. Journal of Clinical Endocrinology and Medicine. 2019;104(10):4295-4303. PMID: 31095302
Amyx MM, Albert PS, Bever AM, Hinkle SN, Owen J, Grobman WA, Newman RB, Chien EK, Gore-Langton RE, Buck Louis GM, Grantz KL. Associations between estimated foetal weight discordance and clinical characteristics within dichorionic twins. The NICHD Fetal Growth Studies. Paediatric and Perinatal Epidemiology. 2019;33(5):332-342. PMID: 3147822700.
Amyx MM, Albert PS, Bever AM, Hinkle SN, Owen J, Grobman WA, Newman RB, Chien EK, Gore-Langton RE, Buck Louis GM, Grantz KL. Intrauterine growth discordance in dichorionic twins. American Journal of Obstetrics and Gynecology, 2019; Aug 24. doi:10.1016/j.ajog.2019.08.02. PMID: 31454510
Tekola-Ayele F, Workalemahu T, Gorfu G, Shrestha D, Tycko B, Wapner R, Zhang C, Buck Louis GM. Sex differences in the associations of placental epigenetic aging with fetal growth. Aging. 2019; 11(15):5412-5432. PMID: 31395791
Ouidir M, Buck Louis GM, Kanner J, Grantz KL, Zhang C, Sundaram R, Rahman ML, Lee S, Kannan K, Tekola-Ayele F, Mendola P. Persistent organic pollutant exposure during early pregnancy and longitudinal fetal growth in the NICHD Fetal Growth Studies - Singletons. JAMA Ped. In Press.
Levine LD, Kim K, Purdue-Smithe A, Sundaram R, Schisterman EF, Connell M, DeVilbiss E, Alkhalaf Z, Radoc J, Buck Louis GM, Mumford SL. Urinary phytoestrogens and menstrual cycle length and variability among healthy eumenorrheic women. Journal of the Endocrine Society. In Press.
Kim S, Chen Z, Perkins NJ, Schisterman EF, Buck Louis GM. A model-based approach to detection limits in studying environmental exposures and human fecundity. Statistics in Biosciences. June 7, 2019. DOI 10.1007/S12561-019-09232-5. In Press.
Honors & Awards
NICHD Collaboration Award, 2017, Eunice Kennedy Shriver National Institute of Child Health & Human Development
Society for Pediatric & Perinatal Research President’s Inaugural Award, 2014, Society for Pediatric & Perinatal Research
NIH Mentoring Award, 2004, National Institutes of Health
Service Award, 2000, International Society for Environmental Epidemiology
Abraham Lilienfeld Award, 1987, Society for Epidemiologic Research