George Mason University
George Mason University Mason
George Mason University

Rosemary Higgins, MD

Associate Dean for Research

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Biography

As Associate Dean for Research, Dr. Rosemary D. Higgins oversees the Office of Research, supports a culture of research in the college, and links the research if the college to the greater university research enterprise.

Prior to coming to Mason, Higgins served as a Medical Officer and the Program Scientist for the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Neonatal Research Network (NRN), a large, multi-investigator, multi-institution network, composed of 15 clinical centers (35 hospitals) and a data coordinating center.  

Her research focuses on neonatal and perinatal medicine.

Degrees

MD, Medicine, Georgetown University

BS, Magna cum laude, Siena College

Research

Research Interests

  • Perinatal and Neonatal Epidemiology
  • Clinical Trials
  • Premature Birth
  • Neonatal Encephalopathy
  • Neonatology
  • Retinopathy of Prematurity

Publications

Brumbaugh JE, Hansen NI, Bell EF, Sridhar, A, Carlo WA, Hintz SR, ...Higgins RD. (2019, March 25). Outcomes of Extremely Preterm Infants With Birth Weight Less Than 400 g. JAMA Pediatrhttps://doi.org/10.1001/jamapediatrics.2019.0180.

Greenberg RG, Chowdhury D, Hansen NI, Smith PB, Stoll BJ, Higgins RD, ...Cotten CM. (2019, Jan 22). Prolonged Duration of Early Antibiotic Therapy in Extremely Premature Infants. Pediatr Res. https://doi.org/10.1038/s41390-019-0300-4.

Watterberg KL, Hintz SR, Do B, Vohr BR, Lowe J, Newman JE, ...Higgins RD. (2018, December 12). Adrenal Function Links to Early Postnatal Growth and Blood Pressure at Age 6 in Children Born Extremely Preterm. Pediatr Res. https://doi.org/10.1038/s41390-018-0243-1. 

Lowe JR, Fuller JF, Do BT, Vohr BR, Das A, Hintz SR, ...Higgins RD. (2019, January). Behavioral Problems Are Associated with Cognitive and Language Scores in Toddlers Born Extremely Preterm. Early Hum Dev. 2019 Jan;128:48-54. https://doi.org/10.1016/j.earlhumdev.2018.11.007

Phelps DL, Watterberg KL, Nolen TL, Cole CA, Cotten CM, Oh W, ...Higgins RD. (2018, Oct 23). Effects of Myo-inositol on Type 1 Retinopathy of Prematurity Among Preterm Infants <28 Weeks' Gestational Age: A Randomized Clinical Trial. JAMA. 320(16):1649-1658.

Shankaran S, Bell EF, Laptook AR, Saha S, Newman NS, Kazzi SNJ, ...Higgins RD. (2019, Jan). Weaning of Moderately Preterm Infants from the Incubator to the Crib: A Randomized Clinical Trial. J Pediatr. 204:96-102.e4. https://doi.org/10.1016/j.jpeds.2018.08.079.

Hintz SR, Vohr BR, Bann CM, Taylor HG, Das A, Gustafson KE, ...Higgins RD. (2018 Jul). Preterm Neuroimaging and School-Age Cognitive Outcomes. Pediatrics,142(1).

Vohr BR, Heyne R, Bann C, Das A, Higgins RD, Hintz SR. (2018 Aug). Development Neonatal Research Network. High Blood Pressure at Early School Age Among Extreme Preterms. Pediatrics, 142(2).

Zhang H, Dysart K, Kendrick DE, Li L, Das A, Hintz SR, ...Higgins RD. (2018 Oct). Prolonged respiratory support of any type impacts outcomes of extremely low birth weight infants. Pediatr Pulmonol, 53(10):1447-1455. https://doi.org/10.1002/ppul.24124.

Vohr BR, Heyne R, Bann CM, Das A, Higgins RD, Hintz SR. ( 2018 Sep). Extreme Preterm Infant Rates of Overweight and Obesity at School Age in the SUPPORT Neuroimaging and Neurodevel-opmental Outcomes Cohort. J Pediatr, 200:132-139.e3. https://doi.org/10.1016/j.jpeds.2018.04.073.

Lakshminrusimha S, Shankaran S, Laptook A, McDonald S, Keszler M, Van Meurs K, Guillet R, Chawla S, Sood BG, Bonifacio S, Das A, Higgins RD. Pulmonary Hypertension Associated with Hypoxic-Ischemic Encephalopathy-Antecedent Characteristics and Comorbidities. J Pediatr. 2018 May;196:45-51.e3. https://doi.org/10.1016/j.jpeds.2017.12.055. Epub 2018 Mar 1.

Adams-Chapman I, Heyne RJ, DeMauro SB, Duncan AF, Hintz SR, Pappas A, Vohr BR, McDonald SA, Das A, Newman JE, Higgins RD; Follow-Up Study of the Eunice Kennedy Shriv-er National Institute of Child Health and Human Development Neonatal Research Network. Neu-rodevelopmental Impairment Among Extremely Preterm Infants in the Neonatal Research Net-work. Pediatrics. 2018 May;141(5). pii: e20173091. https://doi.org/10.1542/peds.2017-3091.

Higgins RD, Jobe AH, Koso-Thomas M, Bancalari E, Viscardi RM, Hartert TV, Ryan RM, Kallapur SG, Steinhorn RH, Konduri GG, Davis SD, Thebaud B, Clyman RI, Collaco JM, Martin CR, Woods JC, Finer NN, Raju TNK. Bronchopulmonary Dysplasia: Executive Summary of a Workshop. J Pediatr. 2018 Jun;197:300-308. https://doi.org/10.1016/j.jpeds.2018.01.043

Lakshminrusimha S, Shankaran S, Laptook A, McDonald S, Keszler M, Van Meurs K, Guillet R, Chawla S, Sood BG, Bonifacio S, Das A, Higgins RD. Pulmonary Hypertension Associated with Hypoxic-Ischemic Encephalopathy-Antecedent Characteristics and Comorbidities. J Pediatr. 2018 Mar 1. pii: S0022-3476(17)31750-X. https://doi.org/10.1016/j.jpeds.2017.12.055

Natarajan G, Shankaran S, Saha S, Laptook A, Das A, Higgins R, ...Walsh M. (2018, Jan 22). Antecedents and Outcomes of Abnormal Cranial Imaging in Moderately Pre-term Infants. J Pediatr. pii: S0022-3476(17)31592-5. https://doi.org/10.1016/j.jpeds.2017.11.036. 

Bajaj M, Natarajan G, Shankaran S, Wyckoff M, Laptook AR, Bell EF, ...Higgins RD. (2018, Jan 3). Delivery Room Resuscitation and Short-Term Outcomes in Moder-ately Preterm Infants. J Pediatr, pii: S0022-3476(17)31595-0. https://doi.org/10.1016/j.jpeds.2017.11.039

Laptook AR, Bell EF, Shankaran S, Boghossian NS, Wyckoff MH, Kandefer S, ...Higgins R. (2018 Jan). Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants. J Pediatr, 192:53-59.e2.

Lakshminrusimha S, Keszler M, Kirpalani H, Van Meurs K, Chess P, Ambalavanan N, ...Higgins RD. (2017 Nov 27). Milrinone in con-genital diaphragmatic hernia - a randomized pilot trial: study protocol, review of literature and survey of current practices. Matern Health Neonatol Perinatol, 3:27. https://doi.org/10.1186/s40748-017-0066-9

Pappas A, Adams-Chapman I, Shankaran S, McDonald SA, Stoll BJ, Laptook AR, Carlo WA, Van Meurs KP, Hintz SR, Carlson MD, Brumbaugh JE, Walsh MC, Wyckoff MH, Das A, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neona-tal Research Network. Neurodevelopmental and Behavioral Outcomes in Extremely Premature Neonates With Ventriculomegaly in the Absence of Periventricular-Intraventricular Hemorrhage. JAMA Pediatr. 2017 Nov 27. https://doi.org/10.1001/jamapediatrics.2017.3545

Travers CP, Carlo WA, Mcdonald SA, Das A, Bell EF, Ambalavanan N, ...Higgins RD. ( 2017 Nov 11). Mortality and Pulmonary Out-comes of Extremely Preterm Infants Exposed to Antenatal Corticosteroids. Am J Obstet Gynecol.  pii: S0002-9378(17)32319-0. https://doi.org/10.1016/j.ajog.2017.11.554

Laptook AR, Shankaran S, Tyson JE, Munoz B, Bell EF, Goldberg RN, ...Higgins RD. (2017). Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial JAMA. 318(16):1550-1560.

Watterberg KL, Fernandez E, Walsh MC, Truog WE, Stoll BJ, Sokol GM, ...Higgins RD. (2017 Sep 7). Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and late preterm newborn infants. J Perinatol.  https://doi.org/10.1038/jp.2017.131.

Greenberg RG, Kandefer S, Do BT, Smith PB, Stoll BJ, Bell EF, ...Higgins RD. (2017 August). Late-onset Sepsis in Extremely Premature Infants: 2000-2011. Pedi-atr Infect Dis J. 2017 Aug;36(8):774-779.

Shankaran S, Laptook AR, Pappas A, McDonald SA, Das A, Tyson JE, ...Higgins RD. (2017, July 4). Effect of Depth and Dura-tion of Cooling on Death or Disability at Age 18 Months Among Neonates With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial. JAMA, 318(1):57-67.

James J, Munson D, DeMauro SB, Langer JC, Dworetz AR, Natarajan G, ...Higgins R. (2017, July 21). Outcomes of Preterm Infants following Discussions about Withdrawal or Withholding of Life Support. J Pediatr. pii: S0022-3476(17)30749-7. https://doi.org/10.1016/j.jpeds.2017.05.056.

Chawla S, Natarajan G, Shankaran S, Carper B, Brion LP, Keszler M, ...Higgins RD. (2017 Jun 6). Mark-ers of Successful Extubation in Extremely Preterm Infants, and Morbidity After Failed Extubation. J Pediatr. pii: S0022-3476(17)30597-8. https://doi.org/10.1016/j.jpeds.2017.04.050

Walsh MC, Bell EF, Kandefer S, Saha S, Carlo WA, D'Angio CT, ...Higgins RD. (2017 Apr 18). Neonatal outcomes of mod-erately preterm infants compared to extremely preterm infants. Pediatr Res. https://doi.org/10.1038/pr.2017.46. 

Srinivasan L, Page G, Kirpalani H, Murray JC, Das A, Higgins RD, ...Cotten CM. (2017 Mar 10). Genome-wide association study of sepsis in extremely premature infants. Arch Dis Child Fetal Neonatal Ed.  pii: fetalneonatal-2016-311545.

Higgins R, Silver R. (2017 Apr). Maternal fever, prematurity and early-onset sepsis. BJOG.124(5):784.

Jensen EA, Dysart KC, Gantz MG, Carper B, Higgins RD, Keszler M, ...Schmidt B. (2017 Feb 28). Association between Use of Prophylactic Indomethacin and the Risk for Bronchopulmonary Dysplasia in Extremely Preterm Infants. J Pediatr. pii: S0022-3476(17)30188-9. https://doi.org/10.1016/j.jpeds.2017.02.003. 

Younge N, Goldstein RF, Bann CM, Hintz SR, Patel RM, Smith PB, ...Higgins RD. (2017 Feb 16). Surviv-al and Neurodevelopmental Outcomes among Periviable Infants. N Engl J Med. 2017 Feb 16;376(7):617-628.

Shankaran S, Laptook AR, McDonald SA, Hintz SR, Barnes PD, Das A, Higgins RD. (2016 Oct 21). Acute Perinatal Sentinel Events, Neonatal Brain Injury Pattern, and Outcome of Infants Undergoing a Trial of Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy. J Pediatr.  pii: S0022-3476(16)30936-2. https://doi.org/10.1016/j.jpeds.2016.09.026. 

Chawla S, Natarajan G, Shankaran S, Pappas A, Stoll BJ, Carlo WA, ...Higgins RD. (2016 Oct 10). Association of Neurodevelopmental Outcomes and Neonatal Morbidities of Extremely Premature Infants With Differential Exposure to Antenatal Steroids. JAMA Pediatr. https://doi.org/10.1001/jamapediatrics.2016.1936.

Denson LA, McDonald SA, Das A, Schendel DE, Skogstrand K, Hougaard DM, ...Higgins RD. (2016 Jul 25). Early Elevation in Interleukin-6 is Associated with Reduced Growth in Ex-tremely Low Birth Weight Infants. Am J Perinatol

Archer SW, Carlo WA, Truog WE, Stevenson DK, Van Meurs KP, Sánchez PJ, ...Higgins RD. (2016 Jul 13). Improving publi-cation rates in a collaborative clinical trials research network. Semin Perinatol. pii: S0146-0005(16)30003-9. https://doi.org/10.1053/j.semperi.2016.05.003

Higgins RD, Shankaran S. (2016 Jun 29). The Neonatal Research Network: History since 2003, future directions and challenges. Semin Perinatol. pii: S0146-0005(16)30002-7. https://doi.org/10.1053/j.semperi.2016.05.002.

Navarrete CT, Wrage LA, Carlo WA, Walsh MC, Rich W, Gantz MG, ...Higgins RD. (2016, June 22). Growth Outcomes of Preterm Infants Exposed to Different Oxygen Saturation Target Ranges from Birth. J Pediatr. pii: S0022-3476(16)30344-4. https://doi.org/10.1016/j.jpeds.2016.05.070. 

Das A, Tyson J, Pedroza C, Schmidt B, Gantz M, Wallace D, Truog WE, Higgins RD. (2016 Jun 22). Method-ological issues in the design and analyses of neonatal research studies: Experience of the NICHD Neonatal Research Network. Semin Perinatol. pii: S0146-0005(16)30005-2. https://doi.org/10.1053/j.semperi.2016.05.005.

Boghossian NS, Hansen NI, Bell EF, Brumbaugh JE, Stoll BJ, Laptook AR, ...Higgins RD. (2016, June). Outcomes of Extremely Preterm Infants Born to Insulin-Dependent Diabetic Mothers. Pediatrics. 137(6). pii: e20153424

D'Angio CT, Ambalavanan N, Carlo WA, McDonald SA, Skogstrand K, ...Higgins RD. (2016, April 23). Blood Cytokine Profiles Associated with Distinct Patterns of Bronchopulmonary Dys-plasia among Extremely Low Birth Weight Infants. J Pediatr. 2016 Apr 23. pii: S0022-3476(16)30002-6. https://doi.org/10.1016/j.jpeds.2016.03.058. 

Boghossian NS, McDonald SA, Bell EF, Carlo WA, Brumbaugh JE, ...Higgins RD. (2016 Apr 18). Association of Antenatal Cortico-steroids With Mortality, Morbidity, and Neurodevelopmental Outcomes in Extremely Preterm Multiple Gestation Infants. JAMA Pediatr. https://doi.org/10.1001/jamapediatrics.2016.0104. 

Phelps DL, Ward RM, Williams RL, Nolen TL, Watterberg KL, Oh W, ...Higgins RD. (2016 Apr 13). Safety and Pharmacokinetics of Multiple Dose myo-Inositol in Preterm. Pediatr Res.  https://doi.org/10.1038/pr.2016.97

Salas AA, Carlo WA, Ambalavanan N, Nolen TL, Stoll BJ, Das A, Higgins RD. (2016 Feb 19). Gestational age and birthweight for risk assessment of neurodevelopmental impairment or death in extremely preterm infants. Arch Dis Child Fetal Neonatal Ed.  pii: fe-talneonatal-2015-309670. https://doi.org/10.1136/archdischild-2015-309670

Higgins RD, Saade G, Polin RA, Grobman WA, Buhimschi IA, Watterberg K, Silver RM. (2016). Evaluation and Management of Women and New-borns With a Maternal Diagnosis of Chorioamnionitis: Summary of a Workshop. Obstet Gynecol. 127(3):426-436.

Wortham JM, Hansen NI, Schrag SJ, Hale E, Van Meurs K, Sánchez PJ, ...Higgins R. (2016). Chorioamnionitis and Culture-Confirmed, Early-Onset Neonatal Infections. Pediatrics. 2016 Jan;137(1):1-11.

Askenazi DJ, Morgan C, Goldstein SL, Selewski DT, Moxey-Mims MM, Kimmel PL, ...Higgins R. (2015 Nov 23). Strategies to improve the understanding of long-term renal consequences after neonatal acute kidney injury. Pediatr Res.  https://doi.org/10.1038/pr.2015.241

Batton B, Li L, Newman NS, Das A, Watterberg KL, Yoder BA, ...Higgins RD. (2015, Nov 13). Early blood pressure, antihypotensive therapy and outcomes at 18-22 months' corrected age in extremely preterm infants. Arch Dis Child Fetal Neo-natal Ed. pii: fetalneonatal-2015-308899. https://doi.org/10.1136/archdischild-2015-308899. 

Weissman SJ, Hansen NI, Zaterka-Baxter K, Higgins RD, Stoll BJ. (2015 Mar 31).Emergence of Antibiotic Resistance-Associated Clones Among Escherichia coli Recovered From Newborns With Early-Onset Sepsis and Meningitis in the United States, 2008-2009. J Pediatric Infect Dis Soc. pii: piv013. 

Shankaran S, McDonald SA, Laptook AR, Hintz SR, Barnes PD, Das A, ...Higgins RD. (2015 Sep 16). Neonatal Magnetic Resonance Imaging Pattern of Brain Injury as a Bi-omarker of Childhood Outcomes following a Trial of Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy. J Pediatr. pii: S0022-3476(15)00869-0. https://doi.org/10.1016/j.jpeds.2015.08.013

Stoll BJ, Hansen NI, Bell EF, Walsh MC, Carlo WA, Shankaran S, ...Higgins RD. (2015). Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012. JAMA 2015;314:1039-51.

Hoffman L, Bann C, Higgins R, Vohr B; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Developmental Outcomes of Ex-tremely Preterm Infants Born to Adolescent Mothers. Pediatrics. 2015 May 11. pii: peds.2014-3880.

Rysavy MA, Li L, Bell EF, Das A, Hintz SR, Stoll BJ, ...Higgins RD. (2015 May 7). Between-hospital variation in treatment and outcomes in extremely preterm infants. N Engl J Med. 372(19):1801-11.

Fernandez E, Watterberg KL, Faix RG, Yoder BA, Walsh MC, Lacy CB, ...Higgins RD. (2015 Mar 31). Definitions of Cardiovascular Insufficiency and Relation to Out-comes in Critically Ill Newborn Infants. Am J Perinatol

Pappas A, Shankaran S, McDonald SA, Vohr BR, Hintz SR, Ehrenkranz RA, ...Higgins RD. (2015). Cognitive outcomes after neonatal encephalopathy. Pediatrics. 135(3):e624-34. https://doi.org/10.1542/peds.2014-1566.

Patel RM, Kandefer S, Walsh MC, Bell EF, Carlo WA, Laptook AR, ...Higgins RD. (2015, Jan 22). Causes and timing of death in extremely premature infants from 2000 through 2011. N Engl J Med. 372(4):331-40.

Hintz SR, Barnes PD, Bulas D, Slovis TL, Finer NN, Wrage LA, ...Higgins RD(2015). Neuroim-aging and neurodevelopmental outcome in extremely preterm infants. Pediatrics. 135(1):e32-42.

Shankaran S, Laptook AL, Pappas A, McDonald SA, Das A, Tyson JE, ...Higgins RD.(2014). Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial. JAMA. 2014;32(24):2629-2639.

Sood BG, Keszler M, Garg M, Klein JM, Ohls R, Ambalavanan N, ...Higgins RD. (2014 Dec 12). Inhaled PGE1 in neonates with hypoxemic respiratory failure: two pilot feasibility randomized clinical trials. Trials ;15(1):486.

Davis AS, Gantz MG, Do B, Shankaran S, Hamrick SE, Kennedy KA, T...Higgins RD. ( 2014 Dec 4). Serial aEEG recordings in a cohort of extremely preterm infants: feasibility and safety. J Perinatolhttps://doi.org/10.1038/jp.2014.217.

Ambalavanan N, Cotten CM, Page GP, Carlo WA, Murray JC, Bhattacharya S, ...Higgins RD. (2014 Nov 6). Integrated Genomic Analyses in Bronchopulmonary Dysplasia. J Pediatr.  pii: S0022-3476(14)00903-2. https://doi.org/10.1016/j.jpeds.2014.09.052. 

Munoz FM, Weisman LE, Read JS, Siberry G, Kotloff K, Friedman J, Higgins RD. (2014 Dec 15). Assessment of safety in newborns of mothers participating in clinical trials of vaccines administered during pregnancy. Clin Infect Dis;59 Suppl 7:S415-27. https://doi.org/10.1093/cid/ciu727.

Ambalavanan N, Carlo WA, Wrage LA, Das A, Laughon M, Cotten CM, Higgins RD. (2014, Nov 25). For the SUPPORT Study Group of the NICHD Neonatal Research Network. PaCO2 in Surfactant, Positive Pressure, and Oxygenation Randomised Trial (SUPPORT). Arch Dis Child Fetal Neonatal Ed. pii: fetalneonatal-2014-306802. https://doi.org/10.1136/archdischild-2014-306802. 

Natarajan G, Shankaran S, Pappas A, Bann C, Tyson JE, McDonald S, ...Higgins R. (2014). Functional status at 18 months of age as a predictor of childhood disability after neonatal hypoxic-ischemic encephalopathy. Dev Med Child Neurol. ;56(11):1052-8.

Kelleher J, Salas AA, Bhat R, Ambalavanan N, Saha S, Stoll BJ, ...Higgins RD. (2014). Prophylactic indomethacin and intes-tinal perforation in extremely low birth weight infants. Pediatrics. 134(5):e1369-77. https://doi.org/10.1542/peds.2014-0183. Epub 2014 Oct 27.

Laptook AR, Kilbride H, Shepherd E, McDonald SA, Shankaran S, Truog W, Das A, Higgins RD. Temperature Control During Therapeutic Hypothermia for Newborn Encephalopathy Using Different Blanketrol Devices. Ther Hypothermia Temp Manag. 2014 Oct 6.

De Jesus LC, Sood BG, Shankaran S, Kendrick D, Das A, Bell EF, ...Higgins RD. (2014, July 18). Antenatal magnesium sulfate exposure and acute cardiorespiratory events in preterm infants. Am J Obstet Gynecol.  pii: S0002-9378(14)00723-6. https://doi.org/10.1016/j.ajog.2014.07.023

Morriss FH Jr, Saha S, Bell EF, Colaizy TT, Stoll BJ, Hintz SR, ...Higgins RD. (2014). Surgery and neurodevelopmental outcome of very low-birth-weight infants. JAMA Pediatr. 168(8):746-54. https://doi.org/10.1001/jamapediatrics.2014.307.

Truog WE, Nelin LD, Das A, Kendrick DE, Bell EF, Carlo WA, Higgins RD. (2014, Jun 5). the NICHD Neonatal Research Network. Inhaled nitric oxide usage in preterm infants in the NICHD neonatal research network: inter-site variation and propensity evaluation. J Perinatol. https://doi.org/10.1038/jp.2014.105.

LeVan JM, Brion LP, Wrage LA, Gantz MG, Wyckoff MH, Sánchez PJ, ...Higgins RD. (2014 May 29). Change in practice after the Surfactant, Positive Pressure and Oxygenation Randomised Trial. Arch Dis Child Fetal Neonatal Ed.  pii: fetalneonatal-2014-306057. https://doi.org/10.1136/archdischild-2014-306057.

Maheshwari A, Schelonka RL, Dimmitt RA, Carlo WA, Munoz-Hernandez B, Das A, ...Higgins RD. (2014, Apr 14). Cytokines associated with ne-crotizing enterocolitis in extremely-low-birth-weight infants. Pediatr Res. https://doi.org/10.1038/pr.2014.48

Stevens TP, Finer NN, Carlo WA, Szilagyi PG, Phelps DL, Walsh MC, ...Higgins R. (2014, Apr 8). Respiratory Outcomes of the Surfactant Positive Pressure and Oximetry Ran-domized Trial (SUPPORT). J Pediatr. pii: S0022-3476(14)00194-2. https://doi.org/10.1016/j.jpeds.2014.02.054. 

D'Angio CT, Murray TE, Li L, Heyne RJ, O'Shea TM, Schelonka RL, ...Higgins RD. (2013). NICHD Neonatal Research Network. Immunogenicity of Haemophilus influenzae type b protein conjugate vaccines in very low birth weight infants. Pediatr Infect Dis J. 32(12):1400-2.

Randolph DA, Nolen TL, Ambalavanan N, Carlo WA, Peralta-Carcelen M, ...Higgins RD. (2014 Feb 19). Outcomes of extremely low birthweight infants with acidosis at birth. Arch Dis Child Fetal Neonatal Ed. https://doi.org/10.1136/archdischild-2013-304179.

Fernandez E, Watterberg KL, Faix RG, Yoder BA, Walsh MC, Lacy CB, ...Higgins RD. (2014 Feb 10). Incidence, Management, and Outcomes of Cardiovascular Insufficiency in Critically Ill Term and Late Preterm Newborn Infants. Am J Perinatol. 

Batton B, Li L, Newman NS, Das A, Watterberg KL, Yoder BA, Faix RG, Laughon MM, Higgins RD. (2014, Feb 6). Evolving blood pressure dynamics for extremely preterm infants. J Perinatol.  https://doi.org/10.1038/jp.2014.6.

Kennedy KA, Wrage LA, Higgins RD, Finer NN, Carlo WA, Walsh MC, ...Phelps DL. (2014 Feb 6). Evaluating retinopathy of prematurity screening guidelines for 24- to 27-week gestational age infants. J Perinatol. https://doi.org/10.1038/jp.2014.12.

DeMauro SB, D'Agostino JA, Bann C, Bernbaum J, Gerdes M, Bell EF, ...Higgins R. (2014, Jan 25). Developmental Outcomes of Very Preterm Infants with Tracheostomies. J Pediatr. pii: S0022-3476(13)01560-6. https://doi.org/10.1016/j.jpeds.2013.12.014.

Boghossian NS, Hansen NI, Bell EF, Stoll BJ, Murray JC, Carey JC, ...Higgins RD. (2014 Jan 20). Mortality and Morbidity of VLBW Infants With Tri-somy 13 or Trisomy 18. Pediatrics

Pappas A, Kendrick DE, Shankaran S, Stoll BJ, Bell EF, Laptook AR, Walsh MC, ...Higgins RD. (2013 Dec 30). Chorioamnionitis and Early Childhood Outcomes Among Extremely Low-Gestational-Age Neonates. JAMA Pediatr. 2013 Dec 30. https://doi.org/10.1001/jamapediatrics.2013.4248. 

Davis AS, Hintz SR, Goldstein RF, Ambalavanan N, Bann CM, Stoll BJ, ... Higgins RD. (2013 Dec 26). Outcomes of extremely preterm infants following severe intracranial hemorrhage. J Perinatol.  https://doi.org/10.1038/jp.2013.162. 

Cotten CM, Goldstein RF, McDonald SA, Goldberg RN, Salhab WA, Carlo WA, ...Higgins RD. (2013). Apolipoprotein E (APOE) Genotype and Outcome in Infants with Hypoxic-Ischemic Encephalopathy (HIE). Pedi-atr Res.  https://doi.org/10.1038/pr.2013.235. 

Lambert BL, Bann CM, Bauer CR, Shankaran S, Bada HS, Lester BM, ...Higgins RD. (2013). Risk-Taking Behavior Among Adolescents with Prenatal Drug Exposure and Extrauterine Environmental Adversity. J Dev Behav Pediatr. 34(9):669-79.

Bell EF, Hansen NI, Brion LP, Ehrenkranz RA, Kennedy KA, Walsh MC, Shankaran S, ...Higgins RD. (2013, Nov 11). Serum Tocopherol Levels in Very Preterm Infants After a Single Dose of Vitamin E at Birth. Pediatrics. 2013 Nov 11.

Wadhawan R, Oh W, Hintz SR, Blakely ML, Das A, Bell EF, ...Higgins RD. (2013 Oct 17). Neurodevelopmental outcomes of extremely low birth weight infants with spontaneous intestinal perforation or surgical necrotizing enterocolitis. J Peri-natol. https://doi.org/10.1038/jp.2013.128. 

Phelps DL, Ward RM, Williams RL, Watterberg KL, Laptook AR, Wrage LA, ...Higgins RD. (2013 Sep 4). Pharmacokinetics and safety of a single intravenous dose of myo-inositol in preterm infants of 23-29 wk. Pediatr Res. https://doi.org/10.1038/pr.2013.162. 

Vohr BR, Stephens BE, McDonald SA, Ehrenkranz RA, Laptook AR, Pappas A, ...Higgins RD. (2013). Extended Hypothermia Follow-up Subcommittee of the NICHD Neonatal Research Network. Cerebral palsy and growth failure at 6 to 7 years. Pediat-rics. 2013 Oct;132(4):e905-14. https://doi.org/10.1542/peds.2012-3915. Epub 2013 Sep 9.

Lowe JR, Duncan AF, Bann CM, Fuller J, Hintz SR, Das A, Higgins RD, Watterberg KL. (2013). Early working memory as a racially and ethnically neutral measure of outcome in extremely preterm children at 18-22months. Early Hum Dev.  doi:pii: S0378-3782(13)00198-9. 10.1016/j.earlhumdev.2013.08.009. 

Natarajan G, Shankaran S, Laptook AR, Pappas A, Bann CM, McDonald SA, Das A, Higgins RD. (2013, Jul 29). Apgar scores at 10 min and outcomes at 6-7 years following hypoxic-ischaemic encephalopathy. Arch Dis Child Fetal Neonatal Ed. https://doi.org/10.1136/archdischild-2013-303692. 

Kumar P, Shankaran S, Ambalavanan N, Kendrick DE, Pappas A, Vohr BR, ...Higgins RD. (2013, Jun 27). Characteristics of extremely low-birth-weight infant survivors with unimpaired outcomes at 30 months of age. J Perinatol.  https://doi.org/10.1038/jp.2013.71. 

Alleman BW, Bell EF, Li L, Dagle JM, Smith PB, Ambalavanan N, ...Higgins RD. (2013). Individual and center-level factors affecting mortality among extremely low birth weight infants. Pediatrics. 2013 Jul;132(1):e175-84. https://doi.org/10.1542/peds.2012-3707. Epub 2013 Jun 10.

Adams-Chapman I, Bann CM, Das A, Goldberg RN, Stoll BJ, Walsh MC, Sánchez PJ, Higgins RD. (2013, May 30). Neurodevelopmental Outcome of Extremely Low Birth Weight Infants with Candida Infection. J Pediatr.  https://doi.org/10.1016/j.jpeds.2013.04.034.

Adams-Chapman I, Hansen NI, Shankaran S, Bell EF, Boghossian NS, Murray JC,...Higgins RD. (2013, Jun 13). Ten-Year Review of Major Birth Defects in VLBW Infants. Pediatrics. 

Batton B, Li L, Newman NS, Das A, Watterberg KL, Yoder BA, Faix RG, Laughon MM, ...Higgins RD. (2013, May 6). Use of Antihypotensive Therapies in Extremely Preterm Infants. Pediat-rics. 

Laptook AR, McDonald SA, Shankaran S, Stephens BE, Vohr BR, Guillet R, Higgins RD, Das A. (2013). Elevated temperature and 6- to 7-year outcome of neonatal encephalopathy. Ann Neurol. 2013 Jan 29. https://doi.org/10.1002/ana.23843. 

De Jesus LC, Pappas A, Shankaran S, Li L, Das A, Bell EF, Stoll BJ, Laptook AR, Higgins RD. (2013 Feb 14). Outcomes of Small for Gestational Age Infants Born at <27 Weeks' Gestation. J Pediatr. https://doi.org/10.1016/j.jpeds.2012.12.097.

Wynn JL, Li L, Cotten CM, Phelps DL, Shankaran S, Goldberg RN, Carlo WA, Higgins RD. (2013 Jan 31). Blood stream infection is associated with altered heptavalent pneumococcal conjugate vaccine immune responses in very low birth weight infants. J Perinatol. https://doi.org/10.1038/jp.2013.5.

Londhe VA, Nolen TL, Das A, Higgins RD, Tyson JE, Oh W, Devaskar SU;. (2013 Jan 17). Vitamin A Supplementation in Extremely Low-Birth-Weight Infants: Subgroup Analy-sis in Small-for-Gestational-Age Infants. Am J Perinatol

Boghossian NS, Page GP, Bell EF, Stoll BJ, Murray JC, Cotten CM, Shankaran S, ...Higgins RD. (2013, Jan 13). Late-Onset Sepsis in Very Low Birth Weight Infants from Singleton and Multiple-Gestation Births. J Pediatr. https://doi.org/10.1016/j.jpeds.2012.11.089. 

Wynn JL, Hansen NI, Das A, Cotten CM, Goldberg RN, Sánchez PJ, ...Higgins RD. (2013). Early Sepsis Does Not Increase the Risk of Late Sepsis in Very Low Birth Weight Neonates. J Pediatr. https://doi.org/10.1016/j.jpeds.2012.11.027.

Vaucher YE, Peralta-Carcelen M, Finer NN, Carlo WA, Gantz MG, Walsh MC, Laptook AR, ...Higgins RD. (2012, Dec 27). Neurodevelopmental outcomes in the early CPAP and pulse oximetry trial. N Engl J Med. 367(26):2495-504.

Bada HS, Bann CM, Whitaker TM, Bauer CR, Shankaran S, Lagasse L, ...Higgins R. (2012 Dec). Protective factors can mitigate behavior problems after prenatal cocaine and other drug exposures. Pediatrics.130(6):e1479-88. https://doi.org/10.1542/peds.2011-3306. Epub 2012 Nov 26.

Shankaran S, Barnes PD, Hintz SR, Laptook AR, Zaterka-Baxter KM, McDonald SA, ...Higgins RD. (2012 Nov). Brain injury following trial of hypothermia for neonatal hypoxic-ischaemic encephalopathy. Arch Dis Child Fetal Neonatal Ed. 97(6):F398-F404.

Stephens BE, Bann CM, Watson VE, Sheinkopf SJ, Peralta-Carcelen M, Bodnar A, ...Higgins RD. (2012). Screening for Autism Spectrum Disorders in Extremely Preterm Infants. J Dev Behav Pediatr. 33(7):535-541.

Natarajan G, Pappas A, Shankaran S, Laptook AR, Walsh M, McDonald SA, Higgins RD, Das A. (2012 Jul 25). Effect of inborn vs. outborn delivery on neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy: sec-ondary analyses of the NICHD whole-body cooling trial. Pediatr Res. https://doi.org/10.1038/pr.2012.103

Shankaran S, Barnes PD, Hintz SR, Laptook AR, Zaterka-Baxter KM, McDonald SA, Eh-renkranz RA, ...Higgins RD. (2012 Jul 17). Brain injury following trial of hypothermia for neonatal hypoxic-ischaemic encephalopathy. Arch Dis Child

Ambalavanan N, Carlo WA, McDonald SA, Das A, Schendel DE, Thorsen P, Hougaard DM, Higgins RD. (2012 Jul 6). Cytokines and Posthemorrhagic Ventricular Dilation in Premature Infants. Am J Perinatol. 

Newman JE, Bann CM, Vohr BR, Dusick AM, Higgins RD; Follow-Up Study Group of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Improving the Neonatal Research Network Annual Certification for Neuro-logic Examination of the 18-22 Month Child. J Pediatr. 2012 Jun 28.

Ambalavanan N, Carlo WA, Tyson JE, Langer JC, Walsh MC, Parikh NA, Das A, Van Meurs KP, Shankaran S, Stoll BJ, Higgins RD; for the Generic Database; Follow-Up Subcommittees of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Outcome Trajectories in Extremely Preterm Infants. Pediatrics. 2012 Jun 11. 

Natarajan G, Shankaran S, McDonald SA, Das A, Ehrenkranz RA, Goldberg RN, Stoll BJ, Tyson JE, Higgins RD, Schendel D, Hougaard DM, Skogstrand K, Thorsen P, Carlo WA. Associ-ation Between Blood Spot Transforming Growth Factor-β and Patent Ductus Arteriosus in Ex-tremely Low-Birth Weight Infants. Pediatr Cardiol. 2012 Jun 10.

Wadhawan R, Oh W, Vohr BR, Saha S, Das A, Bell EF, Laptook A, Shankaran S, Stoll BJ, Walsh MC, Higgins R. Spontaneous intestinal perforation in extremely low birth weight infants: association with indomethacin therapy and effects on neurodevelopmental outcomes at 18-22 months corrected age. Arch Dis Child Fetal Neonatal Ed. 2012 Jun 9.

Tyson JE, Pedroza C, Langer J, Green C, Morris B, Stevenson D, Van Meurs KP, Oh W, Phelps D, O'Shea M, McDavid GE, Grisby C, Higgins R. Does aggressive phototherapy increase mortali-ty while decreasing profound impairment among the smallest and sickest newborns? J Perinatol. 2012 May 31. https://doi.org/10.1038/jp.2012.64. 

Shankaran S, Pappas A, McDonald SA, Vohr BR, Hintz SR, Yolton K, Gustafson KE, Leach TM, Green C, Bara R, Huitema CM, Ehrenkranz RA, Tyson JE, Das A, Hammond J, Peralta-Carcelen M, Evans PW, Heyne RJ, Wilson-Costello DE, Vaucher YE, Bauer CR, Dusick AM, Adams-Chapman I, Goldstein RF, Guillet R, Papile LA, Higgins RD; the Eunice Kennedy Shriver NICHD Neonatal Research Network. Childhood Outcomes after Hypothermia for Neonatal En-cephalopathy. N Engl J Med. 2012 May 31;366(22):2085-2092.

Pappas A, Shankaran S, Hansen NI, Bell EF, Stoll BJ, Laptook AR, Walsh MC, Das A, Bara R, Hale EC, Newman NS, Boghossian NS, Murray JC, Cotten CM, Adams-Chapman I, Hamrick S, Higgins RD. Outcome of Extremely Preterm Infants (<1,000 g) With Congenital Heart Defects From the National Institute of Child Health and Human Development Neonatal Research Net-work. Pediatr Cardiol. 2012 May 30. 

Smith PB, Ambalavanan N, Li L, Cotten CM, Laughon M, Walsh MC, Das A, Bell EF, Carlo WA, Stoll BJ, Shankaran S, Laptook AR, Higgins RD, Goldberg RN; the Generic Database Sub-committee; for the Eunice Kennedy Shriver National Institute of Child Health; Human Develop-ment Neonatal Research Network. Approach to Infants Born at 22 to 24 Weeks' Gestation: Rela-tionship to Outcomes of More-Mature Infants. Pediatrics. 2012 May 28.

Lester BM, Lin H, Degarmo DS, Fisher PA, Lagasse LL, Levine TP, Shankaran S, Bada HS, Bauer CR, Hammond JA, Whitaker TM, Higgins RD. Neurobehavioral disinhibition predicts initiation of substance use in children with prenatal cocaine exposure. Drug Alcohol Depend. 2012 May 17. 

Sood BG, Shankaran S, Schelonka RL, Saha S, Benjamin Jr DK, Sánchez PJ, Adams-Chapman I, Stoll BJ, Thorsen P, Skogstrand K, Ehrenkranz RA, Hougaard DM, Goldberg RN, Tyson JE, Das A, Higgins RD, Carlo WA. Cytokine Profiles of Preterm Neonates with Fungal and Bacterial Sepsis. Pediatr Res. 2012 May 4. https://doi.org/10.1038/pr.2012.56.

Levine TP, Lester B, Lagasse L, Shankaran S, Bada HS, Bauer CR, Whitaker TM, Higgins R, Hammond J, Roberts MB. Psychopathology and Special Education Enrollment in Children With Prenatal Cocaine Exposure. J Dev Behav Pediatr. 2012 Apr 6.

Bliss JM, Wong AY, Bhak G, Laforce-Nesbitt SS, Taylor S, Tan S, Stoll BJ, Higgins RD, Shankaran S, Benjamin DK Jr; Candida Subcommittee of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Candida Viru-lence Properties and Adverse Clinical Outcomes in Neonatal Candidiasis. J Pediatr. 2012 Apr 13. 

Morris BH, Tyson JE, Stevenson DK, Oh W, Phelps DL, O'Shea TM, McDavid GE, ...Higgins RD. (2012 Apr 12). Efficacy of phototherapy devices and outcomes among extremely low birth weight infants: multi-center observational study. J Perinatol. https://doi.org/10.1038/jp.2012.39.

Greenberg RG, Benjamin DK Jr, Gantz MG, Cotten CM, Stoll BJ, Higgins RD, ...Smith PB. (2012 Mar 15). Empiric Antifungal Therapy and Outcomes in Extremely Low Birth Weight Infants with Invasive Candidiasis. J Pediatr. Vohr BR, Stephens BE, Higgins RD, Bann CM, Hintz SR, Das A, ... McGowan EC. (2012 Mar 4). Are Outcomes of Extremely Preterm Infants Improving? Impact of Bayley Assessment on Outcomes. J Pediatr.

Shane AL, Hansen NI, Stoll BJ, Bell EF, Sánchez PJ, Shankaran S, Laptook AR, ...Higgins RD. (2012). Methicillin-Resistant and Suscepti-ble Staphylococcus aureus Bacteremia and Meningitis in Preterm Infants. Pediatrics. 2012 Apr;129(4):e914-e922.

Batton BJ, Li L, Newman NS, Das A, Watterberg KL, Yoder BA, Van Meurs KP, Carlo WA, Higgins RD. (2012, Feb 4). Feasibility Study of Early Blood Pressure Management in Extremely Preterm Infants. J Pediatr

Higgins RD, Raju TN, Edwards AD. In Reply. J Pediatr. 2012 Apr;160(4):709-10.

De Jesus LC, Pappas A, Shankaran S, Kendrick D, Das A, Higgins RD, Bell EF. (2012 Feb 9). Risk Factors for Post-Neonatal Intensive Care Unit Discharge Mortality among Extremely Low Birth Weight Infants. J Pediatr. 

Higgins RD, Devaskar S, Hay WW Jr, Ehrenkranz RA, Greer FR, Kennedy K, Meier P.(2011). Executive summary of the workshop "Nutritional Challenges in the High Risk Infant". J Pediatr. 160(3):511-6.

Natarajan G, Pappas A, Shankaran S, Kendrick DE, Das A, Higgins RD, Laptook AR. (2012 Jan 10). Outcomes of extremely low birth weight infants with bronchopulmonary dysplasia: Impact of the physiologic definition. Early Hum Dev

Carlo WA, McDonald SA, Fanaroff AA, Vohr BR, Stoll BJ, Ehrenkranz RA, ...Higgins RD. (2011 Dec 7). Association of antenatal corticosteroids with mortality and neurodevelopmental outcomes among infants born at 22 to 25 weeks' gestation. JAMA. 306(21):2348-58.

Wynn JL, Tan S, Gantz MG, Das A, Goldberg RN, Adams-Chapman I, Stoll BJ, ...Higgins RD. ( 2011 Dec 5). Outcomes Following Candiduria in Extremely Low Birth Weight Infants. Clin Infect Dis.

Shankaran S, Laptook AR, Tyson JE, Ehrenkranz RA, Bann CM, Das A, Higgins RD. (2011 Nov 1). Evolution of Encephalopa-thy during Whole Body Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy. J Pediatr. 

Ambalavanan N, Carlo WA, McDonald SA, Yao Q, Das A, Higgins RD. (2011 Nov). Identification of Extremely Premature Infants at High Risk of Rehospitalization. Pediatrics. 128(5):e1216-e1225. Epub 2011 Oct 17.

Sant'anna G, Laptook AR, Shankaran S, Bara R, McDonald SA, Higgins RD. (2011 Sep 29). Phenobarbital and Temperature Profile During Hypothermia for Hypoxic-Ischemic Encephalopathy. J Child Neurol

Shankaran S, Das A, Bauer CR, Bada HS, Lester BM, Wright LL, Higgins RD, Poole WK. (2011 Sep). Prenatal cocaine exposure and small-for-gestational-age status: Effects on growth at 6years of age. Neurotoxicol Teratol, 33(5):575-81.

Higgins RD, Raju T, Edwards AD, Azzopardi DV, Bose CL, Clark RH, ...Walsh WF. (2011 Aug 27). Hypothermia and Other Treatment Options for Neonatal Encephalopathy: An Executive Summary of the Eunice Kennedy Shriver NICHD Workshop. J Pediatr. 

Shankaran S, Das A, Bauer CR, Bada HS, Lester BM, Wright LL, Higgins RD, Poole WK. (2011 Aug 15). Prenatal cocaine exposure and small-for-gestational-age status: Effects on growth at 6years of age. Neurotoxicol Teratol. 

Cole CR, Hansen NI, Higgins RD, Bell EF, Shankaran S, Laptook AR, ...Stoll BJ. (2011 Aug 12). Bloodstream Infections in Very Low Birth Weight Infants with Intestinal Failure. J Pediatr

Carlo WA, McDonald SA, Tyson JE, Stoll BJ, Ehrenkranz RA, Shankaran S, ...Higgins RD.(2011 Jul 26). Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Cytokines and Neurodevelopmen-tal Outcomes in Extremely Low Birth Weight Infants. J Pediatr. 

Fisher PA, Lester BM, Degarmo DS, Lagasse LL, Lin H, Shankaran S, ...Higgins R. (2011 Aug). The combined effects of prenatal drug exposure and early adversity on neurobehavioral disinhibition in childhood and adolescence. Dev Psychopathol, 23(3):777-88.

Shankaran S, Pappas A, McDonald SA, Laptook AR, Bara R, Ehrenkranz RA, ...Higgins RD. (2011 July). Predictive Value of an Early Amplitude Integrated Electroencephalogram and Neurologic Examination. Pediatrics, 128(1):e112-e120.

Bauer CR, Lambert BL, Bann CM, Lester BM, Shankaran S, Bada HS, ...Higgins RD. (2011 May 4). Long-Term Impact of Maternal Substance Use during Pregnancy and Extrauterine Environmental Adversity: Stress Hormone Levels of Preadolescent Children. Pediatr Res

Stoll BJ, Hansen NI, Sánchez PJ, Faix RG, Poindexter BB, Van Meurs KP, ....Higgins RD. (2011 May). Early Onset Neonatal Sepsis: The Burden of Group B Streptococcal and E. coli Disease Continues. Pediatrics. 127(5):817-826. Epub 2011 Apr 25.

Shankaran S, Laptook AR, McDonald SA, Higgins RD, Tyson JE, Ehrenkranz RA, ...Walsh MC. (2011 Apr 14). Temperature profile and outcomes of neonates undergoing whole body hypothermia for neonatal hypoxic-ischemic en-cephalopathy. Pediatr Crit Care Med

Laughon MM, Langer JC, Bose CL, Smith PB, Ambalavanan N, Kennedy KA, ...Higgins RD. (2011 Mar 4). Prediction of Bronchopulmonary Dysplasia by Postnatal Age in Extremely Premature Infants. Am J Respir Crit Care Med. 

Shankaran S, Bann C, Das A, Lester B, Bada H, Bauer CR, La Gasse L, Higgins RD. (2011 Mar 17). Risk for obesity in adolescence starts in early childhood. J Perinatol.

Raju TN, Suresh G, Higgins RD. (2011 Mar 7). Patient Safety in the Context of Neonatal Intensive Care: Research and Educational Opportunities. Pediatr Res

Ehrenkranz RA, Das A, Wrage LA, Poindexter BB, Higgins RD, Stoll BJ, Oh W. (2011 Mar 3). for the Eunice Kennedy Shriver National Institute of Child Health Human Development Neonatal Research Net-work. Early Nutrition Mediates the Influence of Severity of Illness on Extremely Low Birth Weight Infants. Pediatr Res.

Wadhawan R, Oh W, Vohr BR, Wrage L, Das A, Bell EF, ...Higgins RD. (2011 Mar). Neurodevelopmental Outcomes of Triplets or Higher-Order Extremely Low Birth Weight Infants. Pediatrics. 127(3):e654-e660. Epub 2011 Feb 28

Higgins RD, Shankaran S. (2011 Jan 31). Hypothermia: Novel approaches for premature infants. Early Hum Dev. 

Askie LM, Brocklehurst P, Darlow BA, Finer N, Schmidt B, Tarnow-Mordi W. (2011 Jan 17). NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol. BMC Pediatr, 11:6.

Whitaker TM, Bada HS, Bann CM, Shankaran S, Lagasse L, Lester BM, Bauer CR, Hammond J, Higgins R. Serial Pediatric Symptom Checklist Screening in Children With Prenatal Drug Expo-sure. J Dev Behav Pediatr. 2010 Dec 31.

Hintz SR, Kendrick DE, Wilson-Costello DE, Das A, Bell EF, Vohr BR, Higgins RD. (2010 Dec 27). Early-Childhood Neurodevelopmental Outcomes Are Not Improving for Infants Born at <25 Weeks' Gestational Age. Pediatrics

Ambalavanan N, Walsh M, Bobashev G, Das A, Levine B, Carlo WA, Higgins RD. ( 2010 Dec 13). Bethesda, MD. Intercenter Differences in Bronchopulmonary Dys-plasia or Death Among Very Low Birth Weight Infants. Pediatrics.

Pappas A, Shankaran S, Laptook AR, Langer JC, Bara R, Ehrenkranz RA, ...Higgins RD. ( 2010 Dec 9). Hypocarbia and Adverse Outcome in Neonatal Hypoxic-Ischemic Encephalopathy. J Pediatr.

Schelonka RL, Maheshwari A, Carlo WA, Taylor S, Hansen NI, Schendel DE, ...Hougaard DM, Higgins RD. ( 2010 Dec 8). T cell cytokines and the risk of blood stream infection in extremely low birth weight infants. Cytokine.

Ang JY, Lua JL, Asmar BI, Shankaran S, Heyne RJ, Schelonka RL,...Higgins RD. ( 2010 Dec). Nasopharyngeal carriage of Streptococcus pneumoniae in very low-birth-weight infants after administration of heptavalent pneumococcal conjugate vac-cine. Arch Pediatr Adolesc Med ;164(12):1173-5.

Lagasse LL, Gaskins RB, Bada HS, Shankaran S, Liu J, Lester BM, Bauer CR, Higgins RD, Das A, Roberts M. Prenatal cocaine exposure and childhood obesity at nine years. Neurotoxicol Tera-tol. 2010 Nov 23. 

Boghossian NS, Hansen NI, Bell EF, Stoll BJ, Murray JC, Laptook AR, Shankaran S, ...Higgins RD. (2010 Dec). Survival and morbidity outcomes for very low birth weight infants with Down syndrome. Pediatrics, 126(6):1132-40. Epub 2010 Nov 22

Carlo WA; Higgins RD. (2010). Optimum Oxygen Therapy to Prevent Retinopathy of Prematurity. Expert Review of Ophthalmology. 5(5): 583-585. 

Kwon JM, Guillet R, Shankaran S, Laptook AR, McDonald SA, Ehrenkranz RA, Tyson JE, O'Shea TM, Goldberg RN, Donovan EF, Fanaroff AA, Poole WK, Higgins RD, Walsh MC. Clini-cal Seizures in Neonatal Hypoxic-Ischemic Encephalopathy Have No Independent Impact on Neurodevelopmental Outcome: Secondary Analyses of Data From the Neonatal Research Network Hypothermia Trial. J Child Neurol. 2010 Oct 4. 

Benjamin DK Jr, Stoll BJ, Gantz MG, Walsh MC, Sánchez PJ, Das A, Shankaran S, Higgins RD, Auten KJ, Miller NA, Walsh TJ, Laptook AR, Carlo WA, Kennedy KA, Finer NN, Duara S, Schibler K, Chapman RL, Van Meurs KP, Frantz ID 3rd, Phelps DL, Poindexter BB, Bell EF, O'Shea TM, Watterberg KL, Goldberg RN; for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Neonatal Candidiasis: Epi-demiology, Risk Factors, and Clinical Judgment. Pediatrics. 2010 126(4):e865-73.Sep 27. 

Bada HS, Bann CM, Bauer CR, Shankaran S, Lester B, Lagasse L, ...Higgins R. (2010 Jun 30). Preadolescent behavior problems after prenatal cocaine exposure: Rela-tionship between teacher and caretaker ratings (Maternal Lifestyle Study). Neurotoxicol Teratol. 

Stoll BJ, Hansen NI, Bell EF, Shankaran S, Laptook AR, Walsh MC, Hale EC, ...Higgins RD. (2010). Neonatal Outcomes of Ex-tremely Preterm Infants From the NICHD Neonatal Research Network. Pediatrics. 126(3):443-56 Aug 23.

Bell EF, Hansen NI, Morriss FH Jr, Stoll BJ, Ambalavanan N, Gould JB, Laptook AR, Walsh MC, Carlo WA, Shankaran S, Das A, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Impact of timing of birth and resident duty-hour restrictions on outcomes for small preterm infants. Pediatrics. 2010 Aug;126(2):222-31. Epub 2010 Jul 19.

Davis AS, Hintz SR, Van Meurs KP, Li L, Das A, Stoll BJ, Walsh MC, Pappas A, Bell EF, Laptook AR, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Seizures in Extremely Low Birth Weight Infants Are Associated with Adverse Outcome. J Pediatr. 2010 Jun 12.

Shankaran S, Bann CM, Bauer CR, Lester BM, Bada HS, Das A, Higgins RD, Poole WK, LaGasse LL, Hammond J, Woldt E. Prenatal cocaine exposure and BMI and blood pressure at 9 years of age. J Hypertens. 2010 Jun;28(6):1166-75.

Neil N. Finer, Waldemar A. Carlo, Michele C. Walsh, Wade Rich, Marie G. Gantz, Abbot R. Laptook, Bradley A. Yoder, Roger G. Faix, Abhik Das, W. Kenneth Poole, Edward Donovan, Nancy S. Newman, Namasivayam Ambalavanan, Ivan D. Frantz III, Susie Buchter, Pablo J. Sánchez, Kathleen Kennedy, Nirupama Laroia, Brenda B. Poindexter, C. Michael Cotten, Krisa P. Van Meurs, Shahnaz Duara, Vivek Narendran, Beena G. Sood, T. Michael O’Shea, Edward F. Bell, Vineet Bhandari, Kristi L. Watterberg, Rosemary D. Higgins, for the NICHD Neonatal Research Network. Early CPAP versus surfactant in extremely preterm infants. New England Journal of Medicine. 2010:362;1970-1979.

Waldemar A. Carlo, Neil N. Finer, Michele C. Walsh, Wade Rich, Marie G. Gantz, Abbot R. Laptook, Bradley A. Yoder, Roger G. Faix, Abhik Das, W. Kenneth Poole, Kurt Schibler, Nancy S. Newman, Namasivayam Ambalavanan, Ivan D. Frantz III, Anthony J. Piazza, Pablo J. Sánchez, Brenda H. Morris, Nirupama Laroia, Dale L. Phelps, Brenda B. Poindexter, C. Michael Cotten, Krisa P. Van Meurs, Shahnaz Duara, Vivek Narendran, Beena G. Sood, T. Michael O’Shea, Edward F. Bell, Richard A. Ehrenkranz, Kristi L. Watterberg, Rosemary D. Higgins, for the NICHD Neonatal Research Network. Target ranges of oxygen saturation in extremely preterm infants. New England Journal of Medicine. 2010:362;1959-1969.

Gaskins RB, Lagasse LL, Liu J, Shankaran S, Lester BM, Bada HS, Bauer CR, Das A, Higgins RD, Roberts M. Small for Gestational Age and Higher Birth Weight Predict Childhood Obesity in Preterm Infants. Am J Perinatol. 2010 Apr 20. 

Lester BM, Lagasse LL, Shankaran S, Bada HS, Bauer CR, Lin R, Das A, Higgins R. Prenatal Cocaine Exposure Related to Cortisol Stress Reactivity in 11-Year-Old Children. J Pediatr. 2010 Apr 16. 

D’Angio CT, Heyne RJ, O’Shea TM, Schelonka RL, Shankaran S, Duara S, Goldberg RN, Stoll BJ, Van Meurs KP, Vohr BR, Das A, Li L, Burton RL, Hastings B, Phelps DL, Sanchez PJ, Carlo WA, Stevenson DK, Higgins RD; on behalf of the NICHD Neonatal Research Network. Hep-tavalent Pneumococcal Conjugate Vaccine Immunogenicity in Very-Low-Birth-Weight, Premature Infants. Pediatr Infect Dis J. 2010 Mar 15.

Higgins RD, Shankaran S, Laptook AR. Hypoxic ischaemic encephalopathy in infants. BMJ. 2010 Feb 9;340:c397. https://doi.org/10.1136/bmj.c397.

Oh W, Stevenson DK, Tyson JE, Morris BH, Ahlfors CE, Bender GJ, Wong RJ, Perritt R, Vohr BR, Van Meurs KP, Vreman HJ, Das A, Phelps DL, O'Shea TM, Higgins RD; On Behalf of the NICHD Neonatal Research Network Bethesda MD. Influence of clinical status on the association between plasma total and unbound bilirubin and death or adverse neurodevelopmental outcomes in extremely low birth weight infants. Acta Paediatr. 2010 Jan 25. 

Higgins RD, Baker CJ, Raju TNK. Executive Summary of the Workshop on Infection in the High Risk Infant. Journal of Perinatology. 2010 Jan 14. 

Hintz SR, Bann CM, Ambalavanan N, Cotten CM, Das A, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Predict-ing time to hospital discharge for extremely preterm infants. Pediatrics. 2010 Jan;125(1):e146-54.

Laptook AR, Shankaran S, Ambalavanan N, Carlo WA, McDonald SA, Higgins RD, Das A; Hypothermia Subcommittee of the NICHD Neonatal Research Network. Outcome of term infants using apgar scores at 10 minutes following hypoxic-ischemic encephalopathy. Pediatrics. 2009 Dec;124(6):1619-26.

Stephens BE, Liu J, Lester B, Lagasse L, Shankaran S, Bada H, Bauer C, Das A, Higgins R. Neurobehavioral Assessment Predicts Motor Outcome in Preterm Infants. J Pediatr. 2009 Oct 30.

Raju TN, Stevenson DK, Higgins RD, Stark AR. (2009). Safe and effective devices and instruments for use in the neonatal intensive care units: NICHD Workshop summary. Biomed Instrum Technol. 43(5):408-18.

Hay WW Jr, Raju TN, Higgins RD, Kalhan SC, Devaskar SU. (2009 Nov). Knowledge gaps and research needs for understanding and treating neonatal hypoglycemia: workshop report from Eunice Ken-nedy Shriver National Institute of Child Health and Human Development. J Pediatr.155(5):612-7.

Lester BM, Bagner DM, Liu J, Lagasse LL, Seifer R, Bauer CR, Shankaran S, ...Higgins RD. (2009). Infant Neurobehavioral Dysregulation: Behavior Problems in Children With Prenatal Substance Exposure. Pediatrics. 124(5):1355-62.

Natarajan G, Shankaran S, McDonald SA, Das A, Stoll BJ, Higgins RD, ...Carlo WA. (2009 Sep 14). Circulating beta chemo-kine and MMP 9 as markers of oxidative injury in extremely low birth weight infants. Pediatr Res

Higgins RD, Shankaran S. (2009 Sep 15). Hypothermia for hypoxic ischemic encephalopathy in infants ≥36weeks. Early Hum Dev. 

Gargus RA, Vohr BR, Tyson JE, High P, Higgins RD, Wrage LA, Poole K. (2009). Unimpaired outcomes for extremely low birth weight infants at 18 to 22 months. Pediatrics. 124(1):112-21.

Ambalavanan N, Carlo WA, D'Angio CT, McDonald SA, Das A, Schendel D, ...Higgins RD. (2009 Apr). Cytokines associated with bronchopulmonary dysplasia or death in ex-tremely low birth weight infants. Pediatrics.123(4):1132-41.

Wadhawan R, Oh W, Perritt RL, McDonald SA, Das A, Poole WK, ...Higgins RD. (2009 Feb). Twin gestation and neurodevelopmental outcome in extremely low birth weight infants. Pediatrics. 123(2):e220-7.

Morris BH, Oh W, Tyson JE, Stevenson DK, Phelps DL, O'Shea TM, ...Higgins RD. (2008 Oct 30). Aggressive vs. conservative phototherapy for infants with extremely low birth weight. N Engl J Med. 359(18):1885-96

Cole CR, Hansen NI, Higgins RD, Ziegler TR, Stoll BJ. (2008 Sep). Very Low Birth Weight Preterm Infants With Surgical Short Bowel Syndrome: Incidence, Morbidity and Mortality, and Growth Outcomes at 18 to 22 Months. Pedi-atrics.122(3):e573-e582.

Laptook A, Tyson J, Shankaran S, McDonald S, Ehrenkranz R, Fanaroff A, ...Higgins RD. (2008 Sep). Elevated temperature after hypoxic-ischemic encepha-lopathy: risk factor for adverse outcomes. Pediatrics. 122(3):491-9.

Levine TP, Liu J, Das A, Lester B, Lagasse L, Shankaran S, ...Higgins R. (2008 Jul). Effects of prenatal cocaine exposure on special education in school-aged children. Pediatrics. 122(1):e83-91.

Hintz SR, Kendrick DE, Vohr BR, Poole WK, Higgins RD. ( 2008 Aug). Community supports after sur-viving extremely low-birth-weight, extremely preterm birth: special outpatient services in early childhood. Arch Pediatr Adolesc Med.162(8):748-55.

Oh W, Perritt R, Shankaran S, Merritts M, Donovan EF, Ehrenkranz RA, ...Higgins RD. (2008 May 8). Association between Urinary Lactate to Creatinine Ratio and Neurodevelopmental Outcome in Term Infants with Hypoxic-Ischemic Encephalopathy. J Pediatr. 

Levine TP, Liu J, Das A, Lester B, Lagasse L, Shankaran S, ...Higgins R. (2008 Jul). Effects of Prenatal Cocaine Exposure on Special Education in School-Aged Children. Pediatrics, 122(1):e83-91.

Tyson JE, Parikh N, Langer J, Green C, Higgins RD. (2008). Intensive Care for Extremely Premature Newborns: Moving beyond gestational age thresholds. New England Journal of Medicine 358(16):1672-1681.

Adams C, Nellie H, Stoll B, Higgins R. (2008 Apr 7). Neurodevelopmental Outcome of ELBW Infants With Posthemor-rhagic Hydrocephalus Requiring Shunt Insertion. Pediatrics.

Bada HS, Langer J, Twomey J, Bursi C, Lagasse L, Bauer CR, ...Higgins R. (2008 Mar 15). Importance of Stability of Early Living Arrangements on Behavior Outcomes of Children With and Without Prenatal Drug Exposure. J Dev Behav Pediatr

Ambalavanan N, Van Meurs KP, Perritt R, Carlo WA, Ehrenkranz RA, Stevenson DK, ...Higgins RD. (2008 Jun). Predictors of death or bronchopulmonary dysplasia in preterm infants with respiratory failure. J Perinatol, 28(6):420-6.

Lee BH, Stoll BJ, McDonald SA, Higgins RD. (2008 Feb). National Institute of Child Health and Human Development Neonatal Research Network. Neurodevelopmental outcomes of extremely low birth weight infants exposed prenatally to dexamethasone versus betamethasone. Pediatrics, 121(2):289-96.

Broitman E, Ambalavanan N, Higgins RD, Vohr BR, Das A, Bhaskar B, ...Carlo WA. (2007 Nov). Clinical data predict neurodevelopmental outcome better than head ultrasound in extremely low birth weight infants. J Pediatr. 151(5):500-5.

Betty R. Vohr, Brenda B. Poindexter, Anna M. Dusick, Leslie T. McKinley, Rosemary D. Higgins. (2007 Oct). Persistent Beneficial Effects of Breast Milk Ingest-ed in the Neonatal Intensive Care Unit on Outcomes of Extremely Low Birth Weight Infants at 30 Months of Age. Pediatrics,120(4):e953-9.

Grave GD, Nelson SA, Walker WA, Moss RL, Dvorak B, Hamilton FA, Higgins R. (2007 Jul 24). New Therapies and Preventive Approaches for Necrotizing Enterocolitis: Report of a Research Planning Workshop. Pediatr Res

Hintz SR, Slovis T, Bulas D, Van Meurs KP, Perritt R, Stevenson DK, Poole WK, Das A, Higgins RD; NICHD Neonatal Research Network. Interobserver reliability and accuracy of cranial ultra-sound scanning interpretation in premature infants. J Pediatr. 2007 Jun;150(6):592-6, 596.e1-5.

Hintz SR, Van Meurs KP, Perritt R, Poole WK, Das A, Stevenson DK, ...Higgins RD. (2007). NICHD Neonatal Research Network.Neurodevelopmental outcomes of prema-ture infants with severe respiratory failure enrolled in a randomized controlled trial of inhaled nitric oxide. J Pediatr,151(1):16-22, 22.e1-3.

Meurs KP, Hintz SR, Ehrenkranz RA, Lemons JA, Ball MB, Poole WK, ...Higgins RD. (2007 June). Inhaled nitric oxide in infants >1500 g and <34 weeks gestation with severe respiratory failure. J Perinatol. 27(6):347-52.

Sheinkopf SJ, Lagasse LL, Lester BM, Liu J, Seifer R, Bauer CR,...Higgins R. (2006). Prenatal cocaine exposure: cardiorespiratory function and resilience. Ann N Y Acad Sci. 2006 Dec;1094:354-8.

Walsh, MC, Laptook, AR, Kazzi, SN, Engle, WA, Yao, Q, Rasmussen, M, ...Higgins, RD. (2007). A Cluster Randomized Trial of Benchmarking and Multimodal Quality Improvement To Improve Survival Free of Bron-chopulmonary Dysplasia in Infants < 1250 grams Birth weight. Pediatrics 2007;119(5):876-90

Higgins RD, Bancalari E, Willinger M, Raju TNK. Executive summary of the workshop on oxygen in neonatal therapies: controversies and opportunities for research. Pediatrics, 2007;119(4):790-6.

Lagasse LL, Hammond J, Liu J, Lester BM, Shankaran S, Bada H, Bauer C, Higgins R, DAS A.Violence and delinquency, early onset drug use, and psychopathology in drug-exposed youth at 11 years. Ann N Y Acad Sci. 2006 Dec;1094:313-8.

Shankaran, S, Lester, B.M., Das, A, Bauer, CR., Bada, HS, LaGasse, LL., Higgins, R. Impact of Maternal Substance Use during Pregnancy on Childhood Outcome. Seminars in Fetal & Neonatal Medicine , 2007 Apr;12(2):143-50.

Bada, HS., Das, A., Bauer, CR., Shankaran, S., Lester, B.M., LaGasse, LL., Hammond, J., Wright, LL., Higgins, R. Impact of Prenatal Cocaine Exposure on Child Behavior through School Age. Pediatrics 2007, 119; (2): e348-e359.

Higgins RD. The Vascular Contribution to Necrotizing Enterocolitis. J Pediatr. 2007 Jan;150(1):5-6.

Namasivayam Ambalavanan, Waldemar A. Carlo, Seetha Shankaran, Carla M. Bann, Steven L. Emrich, Rosemary D. Higgins, Jon E Tyson, T. Michael O'Shea, Abbot R. Laptook, Richard A. Ehrenkranz, Edward F. Donovan, Michele C. Walsh, Ronald N. Goldberg, Abhik Das, for the National Institute of Child Health and Human Development Neonatal Research Network. Predict-ing Outcomes of Neonates Diagnosed With Hypoxemic-Ischemic Encephalopathy. Pediatrics 2006 Nov;118(5):2084-93.

Hintz SR, Kendrick DE, Vohr BR, Kenneth Poole W, Higgins RD, For The NICHD Neonatal Research Network. Gender differences in neurodevelopmental outcomes among extremely pre-term, extremely-low-birth weight infants. Acta Paediatr. 2006 Oct;95(10):1239-48.

Shankaran S, Das A, Bauer CR, Bada H, Lester B, Wright L, Higgins R, Poole K. Fetal origin of childhood disease: intrauterine growth restriction in term infants and risk for hypertension at 6 years of age. Arch Pediatr Adolesc Med. 2006 Sep;160(9):977-81.

Raju TN, Higgins RD, Stark AR, Leveno KJ. Optimizing care and outcome for late-preterm (near-term) infants: a summary of the workshop sponsored by the national institute of child health and human development. Pediatrics. 2006 Sep;118(3):1207-14.

Finer NN, Higgins R, Kattinkel J, Martin RJ. Summary proceedings from the apnea-of-prematurity group. Pediatrics. 2006 Mar;117(3 Pt 2):S47-51.

Higgins RD. 50 Years Ago in The Journal of Pediatrics Incidence of retrolental fibroplasias: Past and present. J Pediatr. 2006 Jun;148(6):778.

Ben H. Lee, Barbara J. Stoll, Scott A. McDonald, Rosemary D. Higgins for the National Institute of Child Health and Human Development Neonatal Research Network. Adverse Neonatal Out-comes Associated With Antenatal Dexamethasone Versus Antenatal Betamethasone. Pediatrics 2006; 117: 1503-1510.

Martin L. B, Jon E. T, Kevin P. L, Scott M, Barbara J. S, David K. S, ...Higgins R.D. Laparotomy Versus Peritoneal Drainage for Necrotizing Enterocolitis or Isolated Intestinal Perforation in Extremely Low Birth Weight Infants: Outcomes Through 18 Months of Adjusted Age. Pediatrics 117(4):e680-7, 2006.

Higgins RD, Raju TNK, Perlman J, Azzopardi DV, Blackmon LR, Clark RH, ...Wyatt J. Hypothermia and perinatal asphyxia: executive sum-mary of the National Institute of Child Health and Human Development workshop. J Pediatr 148:170-175, 2006.

Benjamin DK, Stoll BJ, Fanaroff AA, McDonald SA, Oh W, Higgins RD, Duara S, Poole K, Laptook A. Goldberg R for the NICHD Neonatal Research Network. Neonatal candidiasis among extremely low birth weight infants: risk factors, mortality rate, and neurodevelopmental outcomes at 18 to 22 months. Pediatrics 117:84-92, 2006.

Higgins RD. Hypoxic Ischemic Encephalopathy and Hypothermia: A critical look. Obstetrics & Gynecology. 106(6):1385-1387, December 2005.

Shankaran S, Laptook AR, Ehrenkranz RA, Tyson JE, McDonald SA, Donovan EF, Fanaroff AA, Poole WK, Wright LL, Higgins RD, Finer NN, Carlo WA, Duara S, Oh W, Cotten CM, Stevenson DK, Stoll BJ, Lemons JA, Guillet R, Jobe AH; National Institute of Child Health and Human Development Neonatal Research Network.Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med. 2005 Oct 13;353(15):1574-84.

Higgins RD. Ocular Neovascularization: genomic implications. Current Genomics 2005;6:315-318.

Bada HS, Das A, Bauer CR, Shankaran S, Lester BM, Gard CC, Wright LL, Lagasse L, Higgins R. Low birth weight and preterm birth: etiologic fraction attributable to prenatal drug exposure. J Perinatol 2005, Aug 18.

Blakely ML, Lally KP, McDonald S, Brown RL, Barnhart DC, Ricketts RR, Thompson WR, Scherer LR, Klein MD, Letton RW, Chwals WJ, Touloukian RJ, Kurkchubasche AG, Skinner MA, Moss RL, Hilfiker ML, NEC Subcommittee of the NICHD Neonatal Research Network. Post-operative outcomes of extremely low birth-weight infants with necrotizing enterocolitis or isolated intestinal perforation: a prospective cohort study by the NICHD Neonatal Research Network. Ann Surg 2005;241:984-989.

Stoll BJ, Hansen NI, Higgins RD, Fanaroff AA, Duara S, Goldberg R, Laptook A, Walsh M, Oh W, Hale E for the NICHD Neonatal Research Network. Very low birth weight preterm infants with early onset neonatal sepsis: the predominance of gram-negative infections continues in the NICHD NRN, 2002-2003. Pediatr Infect Dis J 2005;24:635-639.

Krisa P. Van Meurs, M.D., Linda L. Wright, M.D., Richard A. Ehrenkranz, M.D., James A. Lemons, M.D., M. Bethany Ball, B.S., W. Kenneth Poole, Ph.D, Rebecca Perritt, M.S., Rosemary D. Higgins, M.D., William Oh, M.D., Mark L. Hudak, M.D, Abbot R. Laptook, M.D., Seetha Shankaran, M.D., Neil N. Finer, M.D., Waldemar A. Carlo, M.D., Kathleen A. Kennedy, M.D., M.P.H., Jon H. Fridriksson, M.D., Robin H. Steinhorn, M.D., Gregory M. Sokol, M.D., G. Ganesh Konduri, M.D., Judy L. Aschner, M.D., Barbara J. Stoll, M.D., Carl T. D’Angio, M.D., and David K. Stevenson, M.D. for the NICHD Neonatal Research Network. Inhaled nitric oxide for prema-ture infants with severe respiratory failure. New England Journal of Medicine 2005, 353:13-22.

Hintz SR, Kendrick DE, Stoll BJ, Vohr BR, Fanaroff AA, Donovan EF, Poole WK, Blakely ML, Wright LL, Higgins RD for the NICHD Neonatal Research Network. Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing enterocolitis. Pediatrics. 2005 Mar;115(3):696-703.

Higgins RD, Delivoria-Papadopoulos M, Raju T. Executive summary on the workshop on viability. Pediatrics 115:1392-1396, 2005

Hintz SR, Kendrick DE, Vohr BR, Poole WK, Higgins RD, for the NICHD Neonatal Research Network. Changes in neurodevelopmental outcomes at 18 to 22 months’ corrected age among infants of less than 25 weeks’ gestational age born in 1993-1999. Pediatrics 2005;115:1654-51.

Raju TN, Ariagno RL, Higgins R, Van Marter LJ. Research in neonatology for the 21st century: executive summary of the national Institute of Child Health and Human Development-American Academy of Pediatrics workshop: Part I academic issues. Pediatrics 115:468-474, 2005.

Ariagno RL, Van Marter LJ, Higgins R, Raju TN. Neonatology research for the 21st century: Executive summary of the National Institute of Child Health and Human Development-American Academy of pediatrics workshop, Part II training issues. Pediatrics 115:475-479, 2005.

Stoll BJ, Hansen N, Adams-Chapman I, Fanaroff AA, Hintz SR, Vohr B, Higgins RD. (2004). Neurodevelopmental impairment among extremely low birth weight infants with neonatal infection. Journal of the American Medical Association, 292:2357-65, 2004.

Koulo M, Movafagh S, Tuohimaa J, Jaakkola U, Kallio J, Pesonen U, Geng Y, Karvonen MK, Vainio-Jylha E, Pollonen M, Kaipio-Salmi K, Seppala H, Lee EW, Higgins RD, Zukoska Z. Neu-ropeptide Y and Y2-receptor are involved in the development of diabetic retinopathy and retinal neovascularization. Annals of Medicine, 36(3):232-240, 2004.

Higgins RD, Yan Y, Geng Y, Zasloff M, Williams JI. Regression of retinopathy by squalamine in a mouse model. Pediatric Research, 56:144-149, 2004.

Sharma J, Barr SM, Geng Y, Yan Y, Higgins RD. Ibuprofen improves oxygen induced retinopa-thy in the mouse. Current Eye Research, 27:309-314, 2003.

Higgins RD, Yan Y, Geng Y, Sharma J, Barr SM. Captopril and vascular endothelial growth factor in retinopathy. Current Eye Research, 27:123-129, 2003.

Yoon HZ, Yan Y, Gene Y, Higgins RD. Neuropeptide Y expression in a mouse model of oxygen induced retinopathy. Clinical and Experimental Ophthalmology, 30:424-429, 2002.

Higgins RD, Yan Y, Schrier BK. Somatostatin analogues inhibit neonatal retinal neovasculariza-tion. Experimental Eye Research, 74:553-9, 2002.

Tadesse M, Dhanireddy R, Mittal M, Higgins RD. Race, retinopathy of prematurity and Candida sepsis. Biology of the Neonate, 81:86-90, 2002.

Nunes I, Higgins RD, Zanetta L, Shamanian P, Goff SP. cABL is required for the development of hyperoxia-induced retinopathy. J Exp. Medicine, 193:1383-1391, 2001.

Higgins RD, Keszler M. Perinatal vascular development. Cardiovasc Res, 51:7-8, 2001.

Higgins RD, Yan Y, Tadesse M, Yossuck P. Lack of effect of gender on retinopathy in the mouse. Clinical and Experimental Ophthalmology, 29:323-326, 2001.

Tadesse M, Yan Y, Yossuck P, Higgins RD. Captopril improves retinal neovascularization via endothelin-1. Investigative Ophthalmology and Visual Science, 42:1867-1872, 2001.

Yossuck P, Yan Y, Tadesse M, Higgins RD. Dexamethasone alters TNF-alpha expression in retinopathy. Molecular Genetics and Metabolism 72:164-167, 2001.

Yossuck P, Yan Y, Tadesse M, Higgins RD. Dexamethasone and critical effect of timing on retinopathy. Investigative Ophthalmology and Visual Science 41:3095-3099, 2000.

Higgins RD, Sanders RJ, Yan Y, Zasloff M, Williams JI. Squalamine improves retinal neovascu-larization. Investigative Ophthalmology and Visual Science, 41:1507-1512, 2000.

Nandgaonkar BN, Rotschild T, Yu K, Higgins RD. Indomethacin improves oxygen induced retinopathy in the mouse. Pediatric Research, 46:184-188,1999.

Rotschild T, Nandgaonkar BN, Yu K, Higgins RD. Dexamethasone reduces oxygen induced retinopathy in a mouse model. Pediatric Research, 46:94-100, 1999.

Higgins RD, Mendelsohn AL, DeFeo MJ, Ucsel R, Hendricks-Munoz KD. Retinopathy of prematurity: lack of association with prenatal care. J Amer Acad Ped Ophthalmol Strabismus 3:114-116, 1999.

Higgins RD, Yu K, Sanders RJ, Nandgaonkar B, Rotschild T, Rifkin DB. Diltiazem reduces retinal neovascularization in a mouse model of oxygen induced retinopathy. Current Eye Re-search 18:20-27, 1999.

Tyson H, Higgins RD, Tyson I. Family dysfunction and Native American women who do not seek prenatal care. Archives of Family Medicine 8:111-117, 1999.

Mittal M, Dhanireddy R, Higgins RD. Candida sepsis and association with retinopathy of prematurity. Pediatrics 101:654-658, 1998.

Higgins RD, Mendelsohn AL, DeFeo MJ, Ucsel R, Hendricks-Munoz KD. Association of antenatal dexamethasone with decreased severity of retinopathy of prematurity. Archives of Ophthalmology, 116:601-605, 1998.

Higgins RD, Hendricks-Munoz KD, Caines VV, Gerrets RP, Rifkin DB. Hyperoxia stimulates endothelin-1 secretion from endothelial cells and modulation by captopril and nifedipine. Current Eye Research 17:487-493,1998.

Hendricks-Munoz KD, Gerrets RP, Higgins RD, Munoz JL, Caines VV. Cocaine stimulated endothelin-1 release is decreased by ACE inhibitors in cultured human and bovine endothelial cells. Cardiovasc Res 31:117-123, 1996.

Higgins RD. Retinopathy of Prematurity. Resident and Staff Physician 42:66-68, 1996.

Higgins RD, Richter SE, Davis JM. Nasal continuous positive airway pressure facilitates extuba-tion in very low birth weight neonates. Pediatrics 88:999-1003, 1991.

Higgins RD, Phelps DL. Oxygen induced retinopathy: lack of adverse heparin effect. Ped Res 27:580-583, 1990.

Shinwell ES, Higgins RD, Auten RL, Shapiro DL. Routine fiberoptic bronchoscopy in intubated neonates. AJDC 143:1064-1065, 1989.

Honors & Awards

National Institutes of Health Award of Merit, Group Award, 2018, NICHD

National Institutes of Health Award of Merit, Individual Award, 2018, NICHD

National Institutes of Health Award of Merit, Group Award, 2016, NICHD

National Institutes of Health Award of Merit, Individual Award, 2016, NICHD

NIH Director’s Group Scientific/Medical Award for Office of the Director, 2014, NIH

NIH Director’s Individual Scientific/Medical Award for NICHD, 2014, NIH

National Institutes of Health Award of Merit, 2005, 2006, 2008, 2009, 2010, 2012, NICHD

Teacher of the Year, 1993-1994, New York University, Pediatrics Department

Resident Annual Teaching Award, 1987, University of Virginia, Department of Pediatrics

Michael J. Caruso Memorial Award for Humanitarian Service, 1984, Georgetown University

Alpha Kappa Alpha Honor Society, 1980, Siena College

Professional Affiliations

American Academy of Pediatrics, Fellow

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American Medical Association, Member

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Association for Research in Vision and Ophthalmology

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American Academy for the Advancement of Science

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Society for Pediatric Research, Member

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American Pediatric Society

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Schools & Programs